布苯丙胺
布苯丙胺（Dimethoxybromoamphetamine，brolamfetamine，[1]DOB，bromo-DMA）是一种苯丙胺类致幻剂，它最早由亚历山大·舒尔金在1967年合成。[2][3]
药理学
布苯丙胺是5-HT2A、5-HT2B和5-HT2C受体激动剂或部分激动剂。[4]它的致幻效果是由于其对5-HT2A受体的激动剂特性介导的。布苯丙胺还是人类TAAR1受体激动剂。[5]
布苯丙胺在剂量过大时可能会引起弥漫性动脉痉挛。[6]
法律地位
中国大陆
布苯丙胺在中国大陆于2013年被列入精神药品品种目录第一类。
引用文献
- ↑ World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0.
- ↑ Erowid Online Books: "PiHKAL" - #62 DOB
- ↑ Shulgin, A.T.; Sargent, T.; Naranjo, C. (1971). "4-Bromo-2,5-Dimethoxyphenylisopropylamine, a New Centrally Active Amphetamine Analog". Pharmacology. 5 (2): 103–107. doi:10.1159/000136181. PMID 5570923. S2CID 46844380.
- ↑ Ray, T. S. (2010). "Psychedelics and the Human Receptorome". PLOS ONE. 5 (2): e9019. Bibcode:2010PLoSO...5.9019R. doi:10.1371/journal.pone.0009019. PMC 2814854. PMID 20126400.
- ↑ Lewin, A. H.; Miller, G. M.; Gilmour, B. (2011). "Articleid 50034244". Binding Database. 19 (23): 7044–7048. doi:10.1016/j.bmc.2011.10.007. PMC 3236098. PMID 22037049. Retrieved 29 April 2014.
- ↑ Bowen, J. Scott; Davis, Gary B.; Kearney, Thomas E. (1983-03-18). "Diffuse Vascular Spasm Associated With 4-Bromo-2,5-Dimethoxyamphetamine Ingestion". JAMA: The Journal of the American Medical Association (in English). 249 (11): 1477–1479. doi:10.1001/jama.1983.03330350053028. ISSN 0098-7484. PMID 6827726.